Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| THCA | rs10452600 | chr6:26192502 | C/A | 2.21E-8 | 490 | 15.63 | 16.8 | 4.75 | KM Plot |
| THCA | rs10458894 | chr11:3913272 | A/G | 1.25E-5 | 490 | 12.6 | 15.97 | 16.73 | KM Plot |
| THCA | rs1046045 | chr17:57478774 | T/C | 1.03E-5 | 484 | 16.22 | 15 | 15.17 | KM Plot |
| THCA | rs10462577 | chr5:80296433 | T/G | 0.000152 | 478 | 15.93 | 15.27 | 19.08 | KM Plot |
| THCA | rs10483711 | chr14:59761126 | C/T | 1.38E-8 | 488 | 16.37 | 13.5 | 5.45 | KM Plot |
| THCA | rs10483713 | chr14:59762998 | T/C | 1.4E-8 | 488 | 16.38 | 12.62 | 5.45 | KM Plot |
| THCA | rs10483714 | chr14:59785346 | A/G | 1.6E-8 | 486 | 16.37 | 12.7 | 5.45 | KM Plot |
| THCA | rs10484436 | chr6:26237155 | C/T | 3.9E-7 | 485 | 15.32 | 16.72 | 6.67 | KM Plot |
| THCA | rs10484629 | chr6:133117870 | A/C | 7.09E-7 | 486 | 15.87 | 15.7 | 17.77 | KM Plot |
| THCA | rs10488085 | chr7:30087381 | A/G | 0.000108 | 470 | 15.13 | 16.3 | 14.97 | KM Plot |
| THCA | rs10489522 | chr1:41504442 | T/A | 3.73E-12 | 489 | 17.7 | 17.73 | 14.92 | KM Plot |
| THCA | rs10492808 | chr16:20732321 | A/G | 2.39E-5 | 490 | 16.58 | 14.7 | 16.37 | KM Plot |
| THCA | rs10492809 | chr16:20900747 | A/G | 0.000123 | 490 | 17.47 | 14.7 | 16.37 | KM Plot |
| THCA | rs10495123 | chr1:219557659 | C/T | 3.49E-5 | 490 | 15.27 | 19.42 | 12.78 | KM Plot |
| THCA | rs10496748 | chr2:137301605 | G/A | 0.000105 | 477 | 15.48 | 16.95 | 7.8 | KM Plot |